Bourne Foundation NMR Spectroscopy Facility
The Institute for Glycomics' Bourne Foundation NMR Spectroscopy Facility comprises of 400 MHz and 600 MHz nuclear magnetic resonance (NMR) spectrometers, a low-resolution mass spectrometer (LRMS) and a fourier-transform infrared spectrometer (FTIR). This facility comprises a suite of instruments that are utilised for a wide range of applications, including routine organic chemistry or small molecule characterisation, fragment-based drug discovery, high-resolution characterisation of complex organic molecules, and studying binding interactions between ligands and biomolecules, including proteins, viruses, cells or parasites.
Equipment
Bruker Avance III HD Nanobay with a 60-place BACS sample changer and IconNMR automation software
- Key instrument for routine characterisation or structure elucidation of small molecule synthetic and natural products, impurity detection, and fragment-based drug discovery
- Large range of 1D and 2D experiments
- Range of nuclei, including 1H, 13C, 15N, 11B, 19F and 31P
- Temperature range from 25°C to 80°C
Bruker Avance III HD with a cryoprobe and 24-place SampleCase sample changer used with IconNMR automation software or manual control
- High-resolution spectrometer for large molecule or low concentration characterisation or structure elucidation, and biomolecule-ligand interactions
- Large range of 1D and 2D experiments, including STD NMR
- Nuclei include 1H, 13C, 15N
- Instrument can be booked by time (research booking for licensed users) or request specific experiments (service request) via iLab
- Temperature range from 0°C to 75°C
Bruker Alpha-P ATR
- Wide range of applications including: functional group identification, purity analysis, mixture analysis, quantitative analysis, library screening
- Walk-up instrument for licensed users
Internal facility users
Internal, Griffith University users can book our facilities through the iLab application.
External facility users
Anyone external to Griffith University who would like to collaborate with us and access our state-of-the-art facilities can get in touch via e-mail.