Our Research Impact

Going beyond the lab to engage children in STEM

The That’s RAD! Science project is breaking down gender stereotypes and encouraging children to be the scientists of the futu…

Katherine Andrews holding the That's RAD magazine

Bridging the gaps to repair spinal cord injury

An innovative nerve bridge therapy combined with patient-centred rehabilitation is on track to provide people living with spi…

Professor James St John in the lab

Compounds Australia – a unique national facility enabling drug discovery

Discovering a new drug is often achieved by testing large numbers of compounds against a disease – but where do we safely sto…

laboratory equipments in the lab

Tackling complexity in the fight against disease

Systems-based approaches are not only increasing our understanding of disorders such as schizophrenia, but they’re on track t…

Alex Cristino

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GRIDD is a world-class research facility, offering unique resources and drawing on a global network of partners to target the world’s most devastating diseases.

GRIDD is a Griffith University research institute with a focus on early stage and pre-clinical drug discovery. GRIDD’s aim is to utilise its unique resources, dedicated researchers and international partnerships to drive the discovery and development of revolutionary new treatments to improve human health and wellbeing.

We are currently focusing on a number of key discovery areas, including cancer, infectious diseases, Parkinson’s disease, drug resistance and spinal cord injury repair. Innovating at the cutting-edge of both chemistry and biology, we have ongoing established partnerships where we collaborate with local and national health institutions, governments, academia, industry, not-for-profit organisations and communities to create knowledge that transforms lives.

GRIDD is home to two significant resources in Compounds Australia and NatureBank. Compounds Australia is the nations’ industry standard compound curation facility, unmatched in the Southern hemisphere and a leader globally. NatureBank is Australia’s largest collection of raw biota, processed into large extract and fraction libraries. Both resources are available to researchers and industry worldwide that, like GRIDD, are seeking to discover new treatments and cures for debilitating illnesses.

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Join us in the search for treatments for the world's most devastating diseases

Industry, not-for-profit and government partnerships

We extend our heartfelt gratitude to our dedicated partners and supporters, which include but are not limited to:

Additionally, we appreciate the generosity of our community, whose donations play a pivotal role in advancing our quest for novel treatments for cancers, malaria, Parkinson's disease, spinal cord injury and other diseases and health conditions.

At GRIDD, we invite you to explore our world class drug discovery facilities. We regularly organise tours to bring our community beyond the laboratory doors, to showcase our exceptional infrastructure and meet with our research teams.

Directions in drug discovery

Delve deeper into our research and find out more about our approaches, innovation and collaborations across key research areas:

Cancers

An estimated 130,470 new cases of cancer were diagnosed in Australia in 2016, with that number set to rise to 150,000 by 2020. GRIDD research teams are working to discover compounds that are active against a range of cancers, including breast, prostate, pancreatic and brain tumours.

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Infectious diseases

Infectious diseases kill more than one million people annually. GRIDD Professors Kathy Andrews, Vicky Avery and Ronald Quinn are seeking new drugs to treat diseases like malaria and TB, while Associate Professor Tina Skinner-Adams is exploring antiparasitic drug discovery and drug target identification, with a goal to improve the lives of those at risk of parasite infection.

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Neurological disorders

About 70,000 Australians are affected by this progressive disease of the nervous system. Professor George Mellick’s research explores the genetics of Parkinsonism and the interactions between genetic and environmental factors that contribute to onset and development of the disease.

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Drug resistance

Professor Sally-Ann Poulsen has discovered a new way to reverse multidrug resistance in cancer, while Professor Jenny Martin is exploring how to disarm bacteria so they cannot cause disease.

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Spinal cord injury repair

Up to half a million people globally suffer from spinal cord injury. GRIDD’s Associate Professor James St John in the Clem Jones Centre for Neurobiology and Stem Cell Research offers hope of new therapies. The 2017 Australian of the Year, Professor Emeritus Alan Mackay-Sim pioneered this research.

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Our researchers

See the team who make up GRIDD and find out more about our individual research strengths.

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Unique resources

Explore our unrivalled resources available for use

NatureBank

Access NatureBank’s collection of more than 100,000 natural product fractions ready for screening against any disease.

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Compounds Australia

Australia's only dedicated compound management facility, Compounds Australia connects chemists and biologists for drug discovery research.

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Key technologies

Our key technologies include high-throughput screening, Fourier transform mass spectrometry and fragment-based screening.

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Research highlights

Australian of the Year 2017

Professor Emeritus Alan Mackay-Sim

Alan Mackay-Sim is a world-renowned trailblazer in cell transplantation, who paved the way for innovative research to repair damaged spinal cords to return the gift of movement to paralysed people.

Fighting antibiotic resistance

Dr Maria Halili speaks about her work at the Griffith Institute for Drug Discovery finding solutions for antibiotic resistance using disulfide bonds.

Using ion channels to fight Parkinson's Disease

Dr Linlin Ma speaks about her work at the Griffith Institute for Drug Discovery using ion channels in the fight against Parkinson's Disease.

Artificial intelligence in drug discovery

Have you ever wondered how technology can help improve drug discovery research in the future? GRIDD's Dr Miaomiao Liu is working on using artificial intelligence (AI) to analyse natural products for drug discovery in areas such as malaria and tuberculosis.

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